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In the future, more precise tumor cell therapies could be achieved by utilizing nanocarriers, adeno-associated virus (AAV), or lentiviral vectors to deliver functional CUL5 genes to T cells within the tumor microenvironment, or by integrating these approaches into CAR-T cell delivery platforms (153, 154) 9.2 CUL5 and other immune cells Respiratory viral infections upregulate CUL5 expression, which correlates with increased neutrophil infiltration

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ATTAIN-2 (Adults with Obesity and Type 2 Diabetes) ATTAIN-2 enrolled 1,613 adults with both obesity and type 2 diabetes